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Contract Manufacturer Modified Release Tablets

Taste Masking Technology: 

AmWiner Raphe Pharma has expertise in developing and making taste-masked products using fluid bed coating, ion exchange, and other technologies. We have successfully created a taste-masking formula to mask exceedingly unpleasant flavors at less than 40-micron particle sizes.

 Tablet Coated Formulations

 AmWiner Raphe Pharma's formulations are customized to each unique situation. We identify the optimal coating material to establish the optimal system for each project. Our highly trained technicians evaluate all formulation options during this phase to create the final product. The system is then designed to fulfill the desired function and coating material restrictions. The form or variant of the core material is evaluated, along with its particle size, cost, and production requirements.

 Tablet Pressing & Capsule Filling

 Powder can be pressed into various tablet sizes and shapes using a tooling press. Our multiple blending operation styles allow drug distribution throughout the tablet. We can handle any project size, from research to commercial manufacturing, with our 3-station tableting machines.

 Modified Release Technology

 The controlled release mechanism is achieved via a matrix or core-shell structure that offers obstacles to the drug's release. Controlled release of active ingredients is achieved through a matrix or core-shell structure in which the matrix or shell functions as an obstacle. The matrix's porosity, solubility, or erosion property is used to slowly release the active ingredient through the outer coating at a defined rate.

 Encapsulation Fluid Bed Coating

 Since its establishment in 2005, AmWiner Raphe Pharmaceutique has been a leader in fluid bed coating technology. It encapsulates tiny particles in a fluidized bed by creating a cyclic airflow in a differential airflow. Our process differs from other coating procedures in that the nozzle is situated at the bottom of the fluidized bed of particles. When a substance is atomized and sprayed throughout the chamber, a cyclic air stream moves the bed of particles upward as it is coated to form a core-shell composition.

 Process Validation

 There's no product or market in which quality is not essential. A final validation report is prepared once all the required work has been completed, satisfactory results have been achieved, and the procedure is validated for mass production. Raphe has the workforce and resources to accomplish every phase of process validation, from developing a process validation protocol to compiling the final process validation report. Virtually every product in any market and industry considers quality to be necessary.

 When you have a special tablet to bring to the market for commercial distribution, contact us to discuss other technologies available at 469-428-5508

Customized Hair Loss Products, Arthritis Medicines, Yeast Infection Treatments & Smoking Cessation Patches

One size does not fit all in dermatology. Hair loss has so many pathogenesis and everyone should be treated based on the cause of his hair loss. Administrating minoxidil to every hair loss not only creates resistance to testosterone immunostimulatory, but it also creates more hair loss, especially in women. This is why AmWiner developed different types of customized OTC hair loss treatments to target each form of hair loss so that no matter what the cause may be, you will always find a solution. DHT blockers alone have never been the definitive treatment for hair loss. The primary issue of UV-free radical oxidation of the follicular proteins has been under-addressed in most topical treatments. Just as we would protect our skin from UV-sun damage by free radicals, the same way we should protect our scalp from UV ray damage. Pyrithione Zinc offers multiple benefits for treating the inflammatory scalp caused by sun damage and bacteria-fungal infection, and the Zinc component screens the scalp from UV damage like Zinc Oxide used in sunscreens.

When sourcing hair loss treatment products, look for natural product formulations free from petroleum chemicals that deactivate the follicular stem cells, chemical irritants, and synthetic fragrance-free formulas. PG is a good moisturizer and emollient, but when it comes to hair loss, we advise you to use or look for products with a natural moisturizing and conditioning agent like Cocoamidobetaine, Coconut glycerin, and propanediol instead of petroleum chemicals. Using topical solutions containing 0.1% ten to twenty minutes before sun-hit is recommended to help prevent scalp damage, the same way as applying sunscreen twenty minutes before sun exposure is recommended to help prevent skin damage. If you have used DHT blockers for six months and the hair did not grow back, consider treating the scalp condition of follicular inflammation, infection, and UV damage using Pyrithione Zinc herbal and polyphenol extract products. Anti-inflammatories such as Triamcinolone and fluocinolone are very helpful, but whichever pathway you see best, shielding your scalp from sun damage to the follicles, should be the topmost priority.

Minoxidil alone is not a definitive treatment for hair loss because when discontinued, the hair loss continues. This would mean lifetime dependence on treatment to keep the hair hence AmWiner product formulas were combined with other active ingredients that treat other causes of hair loss, present in 70% of women, such as inflammatory scalp and Treatment for Cicatricial alopecia, follicular degeneration syndrome, and clogged pores. The goal is to keep patients healthier and off medication in the shortest possible time, by birthing a pathway of broad-spectrum hair loss treatment that would cover all likely causes of hair loss.

AmWiner manufactures other pharmaceutical OTC products for private label or customized, such as Nicotine Smoking Cessation Patches, also called Nicotine Replacement Therapy (NRT), which includes the branded business and a private label proposition. Both portfolios have a diverse range of products, including patches and lozenges, of different strengths, which aim to help consumers quit their smoking addiction for good. The smoking Cessation patch utilizes a unique Smart Control Technology, which allows for a continuous release of nicotine throughout 24 hours.

Vaginal Yeast Infection, Private label products, are available under your brand with a low minimum quantity or as a customized formula.  All-in-One Vaginal Care for Women, Yeast Infection Treatment, Relieves Pain, Inflammation & Redness, Eliminates Excess Water, Re-Balance Vaginal Flora, Soothing Cooling & Calming, with Anti-Itch Odor Blocking Formula. Maximum strength one-day dosage of 1200mg, extra strength custom two-day dosage of 1000 mg, and regular three-day 600 mg treatments are available upon request, with 5% or 2% 30 grams external cream. Business credits are available. The ingredients and raw materials are organic sourced from suppliers that respect the environment and biodiversity.

Private-label Arthritis Pain relief cream Sodium Diclofenac 1% with 5% Lidocaine External Analgesic, a non-steroidal anti-inflammatory medicine for arthritis with a proven safety profile for arthritis pain, is now available over the counter, formerly a prescription product, it has been trusted by patients and doctors in the U.S. for 10+ years and is non-greasy. An alternative to pills, arthritis pain gel, treats arthritis pain by targeting pain directly at the source to deliver clinically proven nonsteroidal anti-inflammatory medicine for powerful arthritis pain relief with a proven safety profile. Clinically proven to relieve joint pain, reduce stiffness, and improve mobility—a non-greasy and clean scent. Lidocaine and NSAIDs are the key ingredients in this formulation. They work together to provide fast-acting and long-lasting relief from inflammation while minimizing the side effects associated with NSAIDs.

Prescription Strength Tretinoin 0.1% with 5% Hydroquinone private label for healthcare providers for the treatment of acne, melasma, and correct hyperpigmentation in all skin types. Amwiner provides everything a clinical practice needs to offer patients customized care, delivering targeted results and repeat purchases through tailored regimens in preventative and maintenance skin and hair care. The AmWiner system includes over 150 customized products and high-end non-monograph skincare products under your professional brand.

Cold & Flu Cough Syrup Decongestants is a private label for adults and kids. AmWiner manufactures multi-action over-the-counter cold flu syrup for severe cough cold flu decongestant with ibuprofen 250mg and acetaminophen 500mg. Alleviating intra-sinus inflammation is critical to quick recovery from cold and flu. Mint flavor with 12 hours of cooling soothing comfort. Super great taste. No High-Fructose corn syrup. Ibuprofen, as a traditional NSAID, decreases the synthesis of pain- and inflammation, while Acetaminophen, a non-NSAID analgesic, exerts its effects on inhibiting and activating central serotonergic pathways. Working together, the two active ingredients provide 12 hours of harsh pain relief, superior to ibuprofen 250 mg and acetaminophen 650 mg alone. The only COLD FLU syrup that fights pain using two different approaches to maximize efficacy while requiring lower maximum daily doses of each medicine. Only 20 ml per serving is needed to achieve full relief compared to 30 ml of traditional cold flu syrup.  It provides faster relief from cold flu symptoms, and patients can return to work and health faster. Formulated to give patients the benefit of achieving relief by alleviating the inflammation of the bronchial cavity, nostrils, and sinuses, which is absent from the current products in the market today.


 The hair care products are made from naturally sourced ingredients, formulated to address all causes of hair loss from radiation toxins, environmental pollution, UVA-UVB sun rays, seborrheic dermatitis, fungal and bacteria, and more importantly, DHT hormone inhibition by incorporating active pharmacological ingredients, vitamins, and minerals known to grow and prevent hair loss. It works synergistically with minoxidil natural at maximum approved strength to inhibit the hair loss culprit hormones without further hair loss upon discontinuation.


Skincare products are absolute therapy for acne, zits, unwanted pigmentations, and saggy skin and correct fine lines with a specific focus on each skin type and age bracket. The products preserve the quality of the soil, water, and air and avoid pollution, deforestation, and depletion of human and natural resources. They are sustainable, have a low carbon footprint, and are clean beauty skincare and personal care products. Manufactured in FDA FDA-registered and inspected facility compliant with cGMP protocols by professional biochemists. All products are WERCS-OSHA-certified and compliant with California Prop-65, with a 100% guarantee to deliver promises with the highest purity and efficacy. The packaging materials are locally manufactured from recycled materials and are recyclable in cooperation with local communities, respecting each lifestyle.

All products come with a 100% Lifetime Warranty. We replace all third-party product returns at no additional cost to distributors, recall all unsold products 90 days before their expiration dates, and replace them at no extra cost to our distributors. You can rest assured that you will never lose a dime selling or distributing any product they manufacture.


Drug store buyers turn to Amwiner for these products: 1: Allergy Nasal Decongestant Spray Oxymetazoline hydrochloride (0.05%) nasal sprays. Maximum strength relief from mild to moderate asthma allergy congestion and inflammation attacks. Formulated with a base distillate of Yerba Santa, Mullein, and elecampane root extracts, a natural anti-inflammatory agent for longer-duration relief and hyaluronic acid for extra moisturizing. No drip severe congestion maximum strength 12-hour nasal congestion relief spray provides fast, powerful, medicated relief of asthma nasal congestion, colds, or allergies. Formulated to work instantly, allowing more straightforward nose breathing without unpleasant wheezing.


2: Mometasone furoate monohydrate (glucocorticoid) 50 mcg Emergency Airway Decongestant The mometasone furoate 50 mcg spray offers the same prescription strength relief over the counter for 24 hours. Instant relief of multiple allergy symptoms such as nasal congestion, runny nose, sneezing, and itchy nose. This odor-free mist spray is the

way to deliver non-drowsy allergy medicine directly to the site of congestion. A trusted active ingredient for all day and night, relief of seasonal allergy symptoms. It is not recommended for use in children, and long-term use is not encouraged for the risk of glaucoma and cataracts.


3: Phenylephrine Hcl 1.0% Non-Drowsy Fast Acting decongestants and Ephedrine Sulfate 25mg Bronchodilator Relief of Mild intermittent Asthma Symptoms Caplets


 4: Minoxidil hair loss treatment tablets, finasteride tablets, spironolactone, and over-the-counter self-care are used for hair loss. The company is the third Pfizer and Perrigo qualified FDA facility vendor, manufacturing generic prescription tablets, capsules, and liquid oral dosage medications.

 AmWiner offers customized Hair Loss treatment.

 Clascoterone and CB-03-01 Formula for Psoriasis Hair Loss, Frontal Fibrosing Alopecia, Cicatricial Alopecia, Inflammatory Scalp Disorder, Folliculitis Decalvan, Scalp Nodules and Papules, Bacterial Folliculitis, Sycosis Barbae, Scarring Alopecia, And Scalp Dermatitis. DALOSIRVAT, SM04554, and SETIPIPRANT formula, the absolute for hair loss caused by telogen effluvium or certain diseases like thyroid insufficiency, thalassemia, and HIV. Hair loss from side effects of medications, birth control pills, behaviors like trichotillomania, nutritional deficiency, traction alopecia, and rapid weight loss. The Next Big Thing in Hair Loss Restoration with RU58841 and Dutasteride. The Product of choice for hair loss induced by radiation therapy, progesterone deficiency, prolonged hospital stay hair loss, stress induces hair loss, non-genetic hair loss, hair loss not associated with any known causes, hair loss from autoimmune diseases and syndromes, emotional distress, exposure to toxins, Lichen planopilaris, viral infections such as herpes zoster and herpes simplex, appendage tumors, patchy, circular, or oval hair loss with distinct edges hair loss in men and women. The Next Generation Hair Loss Treatment Bimatoprost & Minoxidil Sulphate 5% Solution. Bimatoprost, a prostaglandin F2-analog, has proved a great success in treating eyelash and scalp alopecia. Bimatoprost is a medication that is effective in the treatment of glaucoma and other conditions of the eye. The FDA also approves it for treating hypotrichosis, sparse or thinning eyelashes. In recent years, bimatoprost has been used off-label for hair growth. It helps with follicular syndrome, folliculitis, cicatricial alopecia in women, chemical and environmental pollution hair loss, pregnancy-induced hair loss, UV radical hair loss treatment, and for use in men over 50 who do not respond to traditional minoxidil solutions or experienced hair loss for over seven years.


 For more information, email: or Call: 1-469-428-5508

AmWiner Unleashes the Power of AI in Skincare Medicines, Drug Product Development, and Efficacy Testing

Over the years, the pharmaceutical industries have witnessed a remarkable transformation with the integration of Artificial Intelligence (AI) in medicine development and efficacy testing. The use of AI has revolutionized the way skincare medicines are formulated, dosed, and tested for stability and efficacy. AmWiner Brain Wise Research Institute became the first pharmaceutical manufacturing company to utilize the power of artificial intelligence tools in drug product development.


The Challenges in pharmaceutical drug formulation have increased significantly in recent decades, while at the same time the market situation has grown increasingly challenging. New chemical entities in the pipeline are facing solubility challenges, with about 80 percent of them reported as having poor solubility. Since formulation solubility is a critical prerequisite for good bioavailability and therapeutic efficacy, finding ways to improve solubility without changing the chemical nature of the NCE has never been more important. 

In addition, the current industry trends towards regionalization and personalization of treatment approaches necessitate faster, more efficient, and increasingly flexible solutions. As a result, continuous pharmaceutical manufacturing is currently in a prominent field of development, driving the need for tighter process controls and more thorough process and product understanding. An intelligence technology having access to a wide range of suitable excipients is a prerequisite for a successful formulation approach, and this is what we offer to all pharmaceutical industries.

.Drug formulation development challenges for small biopharmaceutical companies are becoming increasingly important as drivers of innovation in drug development. It has recently been estimated that most drugs currently in development are in the hands of small biopharmaceutical companies. Formulation is one of the most crucial parts of the drug development process. We must be able to deliver the drug to the body in whatever dosage form necessary that provides the best effect for that medication. Without proper formulation that guarantees solubility and bioavailability, patients’ health and healthcare system will be at tremendous risk. The small pharmaceutical drug companies want to quickly develop formulations for clinical trials, at the same time, but they have reduced resources and technology challenges to develop the most cost- effective formulation as quickly as possible, the quicker the medication can make its way to patients, the faster we can impact the worlds healthcare system.

.The two parameters; time and cost are the biggest challenges in formulation development, especially of small molecules. This means how well that formulation releases the molecule and how well that molecule passes from the gastrointestinal tract into the systemic circulation will determine the therapeutic outcome. And this process is less efficient when drug solubility is reduced. And what we've seen over the past decades is that the solubility of drug molecules has been decreasing on yearly basis, that up to 80% of the drugs in the drug development pipeline are poorly soluble. Poor soluble drugs in the system means longer patient recovery time. An intelligence technology having access to a wide range of suitable excipients is a prerequisite for a successful pharmaceutical drug developer. 

.Small pharmaceutical companies have used a variety of approaches to address these drug formulation challenges, including the use of new technical platforms, the use of new formulations or technologies that enhance the actions of known drugs. One example is a new, thermostable polymer for hot-melt extrusion processes that combines stabilization of the solid amorphous form in the tablet and inhibition of drug precipitation in dissolution. Another formulation technology being used is a silica-based drug carrier that features a functionalized particle structure that allows for API adsorption onto its surface and pores, stabilizing the drug in a soluble amorphous form. These two methods have not yielded a definitive success that the need for intelligent technology capable of guaranteeing effective formulation will help strengthen and improve our healthcare system and patients’ wellbeing.


.Over the years, AmWiner & Raphe Holdings forecasted a remarkable transformation of pharmaceutical industry in drug development and patient care with the integration of Artificial Intelligence (AI) in medicine development and efficacy testing. The use of AI will revolutionize the way drug products are formulated, dosed, and tested for stability and efficacy. 

.Understanding  AI PHARMA Technology is a field of artificial intelligence (AI) in which software learns from imputed data to perform a task throughout the drug development and manufacturing process that will increase drug efficiency and effectiveness, decreasing the time and cost required to bring new drugs to market. Giving small pharmaceutical companies the opportunity to be part of the manufacturing process of bringing new drugs with optimum solubility and bioavailability to the market and increasing the supply of the existing ones. These improvements will save lives and reduce suffering by getting drugs to patients in need more quickly and could allow researchers to invest more resources in areas such as rare or orphan diseases. 

AmWiner`s .AI PHARMA Technology significantly enhance the process of medicine development by taking the guesswork out of every formulation. The chemist/pharmacist will know with 100% certainty the best and accurate percentage of Active Pharmacological Ingredient/s and expedient percentages to use his/her formulation that will yield the desired expected results, taking the human error of miscalculation that contributes to some adverse effects. When confronted with a custom formula, you`re confident that the technology will determine the accurate percentage of the active and expedients needed to use based on the imputed objective you intend to achieve. Even when you add any ingredient more or less of what is required, the “AI PHARMA Technology indicates which ingredient/s you have in excess and what to do to balance your formulation, expediting the formulation and optimizing the dosages.

.Through advanced algorithms of the AI PHARMA technology for pharmaceutical industries analyzes the finished product to produce a more accurate certificate of analysis and SDS document, conduct stability product testing, shelf-life test, and efficacy testing. AmWiner's “AI PHARMA Technology” takes the guesswork out when conducting Quality control testing on solid oral dosage tablets/capsules, friability tests, tablet disintegration tests, dissolution tests, and moisture content tests. This tool is a power engineer in tablet coating when manufacturing XR or enteric-coated pills. It determines the exact percentage of the coating ingredient required and should show the best coating substance suitable for each tablet moiety. You (the chemist) can take the drying and chipping issues of the coating process out of your list of worries because this technology delivers 100% accurate coating technique and guide for your OSD batches.

.AmWiner's “AI PHARMA Technology collects vast amounts of data related to human biology, dermatological conditions, and ingredient interactions to identify potential compounds, ingredients, and therapeutic interventions necessary for every skincare or bodily concern. This not only accelerates the research and development phase but also enables the creation of highly effective and personalized solutions. Moreover, these AI algorithms predicts the performance of different formulations, leading to the creation of products that offer superior outcomes in addressing various patients’ skin concerns.

.The integration of AmWiner AI PHARMA Technology in pharmaceutical product development facilitates the identification of novel compounds with therapeutic potential. By analyzing molecular structures and biological pathways, these AI algorithms pinpoint promising treatments for any skincare or bodily issues, thus streamlining the therapeutic process. This approach opens new avenues for developing innovative treatments for common skin and body ailments, such as acne, vitiligo, rosacea, pigmentation, eczema, and aging-related conditions and enable researchers to assess the safety and efficacy of potential drug products, fostering the creation of products that are not only effective but also safe for prolonged use.

.In essence, AmWiner AI PHARMA Technology revolutionizes pharmaceutical drug development by empowering researchers to navigate the complexities of human biology and formulation optimization with unprecedented speed and precision. The insights generated by the algorithm will pave the way for the creation of next- generation drug products that cater to diverse health conditions, marking a paradigm shift in the field of dermatology and general medicine.

 The Role of AmWiner AI PHARMA Technology” in Medicine Dosing. In the realm of drug product development, accurate dosing is paramount to ensure optimal therapeutic outcomes and minimize adverse effects. AmWiner Pharmacy AI technology” plays a pivotal role in precision dosing by leveraging data analytics and predictive modeling to determine the most effective dosage regimens for any drug product. By analyzing patient-specific factors, such as skin type, age, and medical history, the AmWiner AI algorithms can tailor dosing recommendations to individual needs, thereby enhancing the efficacy and safety of treatments. This technology adapts to real-time changes in patient responses and adjust dosage parameters accordingly. This dynamic dosing approach enables the healthcare professionals to fine-tune treatment plans based on evolving patient conditions, ultimately optimizing the therapeutic benefits of the medicines. Additionally, the AI algorithms identify potential drug interactions and contraindications, offering valuable insights to healthcare providers and patients alike.

.By harnessing the power of AmWiner AI PHARMA technology” in medicine dosing, the pharmaceutical industry is poised to deliver personalized treatment regimens that are tailored to everyone’s unique physiological and dermatological profile. This not only maximizes the efficacy of the drug product but also minimizes the risk of adverse reactions, setting a new standard for precision and safety in dermatological care.

.Utilizing AmWiner “AI PHARMA Technology” for Product Stability Testing. Ensuring the stability of any drug product is essential to maintain its efficacy and safety over time. This AI technology emerge as a game-changer in product stability testing, enabling manufacturers to assess the impact of various environmental factors, storage conditions, and formulation changes on the shelf-life and performance of skincare products. Through predictive modeling and accelerated testing methodologies, the algorithms predict the degradation kinetics of active ingredients, anticipate potential formulation instabilities, and optimize packaging materials to prolong product shelf-life.

.The AI-powered stability testing moiety allows for the rapid identification of formulation modifications that can enhance product stability without compromising efficacy. By simulating different storage scenarios and analyzing real-time data from stability studies, these AI algorithms recommend adjustments to formulation parameters, packaging designs, and storage protocols to mitigate degradation risks and extend the lifespan of drug products. This proactive approach to stability testing minimizes product wastage and ensures consistent efficacy throughout the product's shelf-life, thereby enhancing customer satisfaction and brand reputation.

. Furthermore, it facilitates the early detection of stability issues by flagging potential risks based on predictive analytics and historical data. This proactive monitoring capability empowers drug product manufacturers to preemptively address stability concerns, implement corrective measures, and maintain the integrity of their products throughout their lifecycle. As a result, the AI-driven stability testing not only streamlines the product development process but also fosters the creation of high- quality drug products that meet stringent stability and performance standards.

.Incorporating AmWiner AI PHARMA Technology” in product development: Best practices. To maximize the benefits of this AI, compounding pharmacist and chemists will prioritize data quality and diversity, ensuring that the AI algorithms collect comprehensive datasets that encompass a wide range of demographics, and dermatological conditions. This inclusive approach to data collection and analysis will foster the creation of effective drug products across diverse populations and demographics, promoting inclusivity and accessibility in healthcare systems. By fostering partnerships between dermatologists, pharmacologists, data scientists, and AI experts, drug product developers can leverage diverse expertise to optimize formulation strategies, dosing protocols, and efficacy testing methodologies. This collaborative approach not only enriches the insights generated by the AI algorithm but also ensures that drug products are developed with a comprehensive understanding of human biology, therapeutic mechanisms, and patient needs.

. Continuous validation and refinement of Amwiner`s AI PHARMA technology models are critical to maintaining the accuracy and reliability of drug development processes. The chemist/pharmacist will regularly validate the AI algorithms against real-world clinical data, patient outcomes, and market feedback to ensure that the insights and recommendations offered by AmWiner remain aligned with actual patient needs and treatment outcomes.

.To develop a drug product with high precision and efficacy or to explore cutting-edge solutions in dermatology, call us at: 1-469-428-5505 or email QCTEAM@AMWINER.COM visit our website or

AmWiner Bag-On-Valve Technology System

AmWiner Bag-on-valve (BOV) technology system is a hygienic and reliable form of packaging technology with several advantages over conventional aerosol canister spray of foam packaging. The product constituents are placed separate from the base ingredients, upholding the product’s purity. This technology also protects the aerosol or aerofoam from oxidation, protects it from heat and secondary pollution. BOV’s introduction to aerosol canister packaging is a progressive innovation that outdoes its predecessors on arguably all fronts. As such, it suffices to say that it is here to stay, and soon, it will render conventional aerosol canisters obsolete.

One of the main aspects of BOV is the safety and environmental benefits. This is because no flammable propellants are needed, just environmentally friendly gases or your base product ingredients. The aluminum bags ensure that the formulation is hermetically sealed. This prevents contamination and oxidation of the active ingredients to the last pump, which also contributes to the durability of the products without preservatives.


In traditional canister aerosol, the product is mixed with propellant and preservatives, rendering it not pure enough to enhance the products` quality. Excessive preservative in hair care products to prolong the shelf life is one of the culprits for hair loss seen in men and women. Besides, the poor sealing mechanism can lead to the product’s contamination by bacteria and other gases, which might reduce the product’s overall shelf-life. In traditional aerosol canister, you can only use about 95% of the product stored in a canister, but with BOV aero foam technology you can use the entire contents, leaving no room for waste or negative environmental impact. BOV allows complete product emptying, leaving no product in the container.

Sealing performance: When it comes to BOV, we utilize a multi-level protective system comprising a tinplated steel can (or aluminum), aerosol valve components, and four-layer vacuum pouches which separates the active ingredients from the rest of the ingredients in the product. On the other hand, conventional aerosol canisters do not have the best sealing performance, nor do they have a bag to safeguard the product’s integrity.

Hygienically clean: Separated and Yet Together. The difference between conventional aerosol technology and AmWiner BOV system is that with the conventional variant the product and propellant are in the can together with no separation. With the BOV technology, the active ingredients and the product base are separated in the can. The active ingredient is contained in a separate flexible bag, which is connected to the valve, and the compressed gas and other base ingredients is in the remaining space between the bag and the side of the can. When the actuator nozzle is pressed, the pure product is dispensed together though separately on your palm.

AmWiner offers the BOV system as private label optional packaging to distributors of Minoxidil hair loss treatment foam with minimum of 150,000 units per order. There is a 40% deposit required with a 60% balance spread out over a period of 12 months. It is not only an excellent dispensing system, but a sustainable packaging process that also helps reduce our ecological footprint, improves the product efficacy and shelf life, and with no entry of environmental oxygen or nitrogen, the oxidative process of formula breakdown is eliminated resulting in a more potent product with longer duration shelve life.




AmWiner; the pharmaceutical vendor of Perrigo, and Johnson & Johnson, works tirelessly to make future a reality for patients everywhere, by alleviating skincare problems with science, improving healthcare products with ingenuity, and healing hopelessness with love. To make the greatest impact, AmWiner collaborates with experts at every stage, from early discovery to market access.

In 2016, AmWiner acquired Guangzhou Pharmaceutical Technology Co Ltd manufacturing 100% pure minoxidil raw powder, and active pharmaceutical fermenting plant in Guangzhou, to enable them offer reduced cost for minoxidil hair loss treatment products for Perrigo, and Johnson & Johnson. The Company manufactures chemical medicines, pharmaceutical raw materials, medical devices, chemical reagents, and health-care products for hospitals and drug stores. They are FDA ANDA-licensed (ANDA075357) and approved pharmaceutical company, providing vendor manufacturing services to Perrigo for Minoxidil Hair Loss Treatment. AmWiner has several Locations in Israel, Guangzhou China, Canada, And United States, providing private Label, contract manufacturing and customized hair loss treatments products for Cosco, Amazon, HEB, Kroger and Drug Stores in United States.

But minoxidil alone is not a definitive treatment to hair loss, because when discontinued, the hair loss continues. This would mean lifetime dependence on treatment, to keep the hair, hence AmWiner product formulas were combined with other active ingredient that treats other causes of hair loss, present in 70% women, such as inflammatory scalp and Treatment for Cicatricial alopecia, follicular degeneration syndrome, and clogged pores. The goal is to keep patients healthier and off medication in the shortest possible time by birthing a pathway of broad-spectrum hair loss treatment that would cover all likely causes of hair loss. 

AmWiner manufactures other pharmaceutical products such Minoxidil hair loss treatment tablets, finasteride tablets, Spironolactone, and Self-care over-the-counters used for hair loss, allergies, pain, Melasma treatment, and pigmentations. The company is the third vendor Pfizer qualified pharmaceutical company and FDA approved ANDA holding facility for generic prescription tablets, capsules, and liquid oral dosage medications.

 AmWiner offers customized dermatology products for hair Loss treatment such as 5% Minoxidil with Spironolactone 100mg and Finasteride 01% solution concentration for professional hair loss treatment. The solution of Minoxidil, Spironolactone and Finasteride is a proven hair loss treatment that helps promote blood flow to the scalp and can help regrow hair and keep the growth with confidence. Spironolactone is a diuretic that helps reduce hair loss from the scalp and helps reduce the amount of DHT in the blood. Finasteride helps to block the production of DHT, which is the hormone that causes hair loss. All three of these combination solutions are available for private label distribution. 

AmWiner Raphe Holdings is state of TX licensed manufacturing laboratory with headquarters located in Dallas TX, providing private label and contract manufacturing of hair loss products and full wide range of dermatology skincare with sustainable low carbon footprint self-care products, Clean Beauty skincare, natural analgesics, hair care, and personal care products. 

Offers the preferred products of choice for failed hair transplant, customized products for medical practice, treatments for shiny scalp & rigid scalp hair loss in young and older adults with resistant testos-hormones alopecia. AmWiner recalls all unsold orders 90 days prior to expiration & replaces them with fresh batches at no additional cost. Their products come with customized high-end packaging & marketing brochures & flyers included. 60ml & 100ml sizes available with low unit price range of $4.39 - $7.69. AmWiner is FDAs approved facility for ANDA minoxidil hair loss treatment medications, self-care products, OTC drugs, & generic prescriptions-with customized skin care medications for dermatologists’ options. 

For wholesale distribution of any of Raphe Pharmaceutique, Go to or or call 1-469-428-5508

Hair Regrowth Treatments Guide: AmWiner`s physicians recommend hair loss treatment that yields result without the risk of hair falling off upon discontinuation, look for minoxidil products that contain other ingredients such as: acetyl tyrosine, pyrithione, selenium sulfide, ketoconazole, biotin, fluocinolone, melatonin, saw palmetto, finasteride, vitamin e, and caffeine. 

AmWiner Hair loss treatment centers offer significant alternative to hair transplant surgeries, for inflammatory scalp and scarring alopecia in women, treatments for follicular degenerate scalp syndrome, with products that purge clogged scalp pores, rebuild follicular protein cascade & protein synthesis. Customized treatments hair loss formula available for dermatologists & hair surgeons, broad spectrum hair loss treatments to cover chemical & pregnancy induced hair loss, and hormone related hair loss treatment. Physicians preferred choice for men’s treatment are the formula with 0.1% finasteride, Minoxidil 5% with 5% S.Equol and ketoconazole. Progesterone and estradiol hair loss formula are available for treating hair loss caused by decreased progesterone or estradiol hormones in men.

The company offers Net Credit to store buyers and distributors nationwide with monthly supply capacity of 330,000 units per month per product line for Vitiligo Melasma and Hair Loss treatment product lines.

 AmWiner ingredients and raw materials are organically sourced from suppliers that respect the environment and biodiversity. Their health and beauty brands include high-quality branded and private-label non-prescription cosmetics, health and beauty products, manufactured under high standard GMP protocols with no child or minor labor utilized, respecting the normal working hours and international labor conventions.

The packaging materials are locally manufactured from recycled materials and are recyclable in cooperation with local communities respecting each lifestyle. AmWiner is one of the premiere Minoxidil manufacturer in Israel, Canada, and United states.  AmWiner private label a large range of dermatological products and the best effective treatment of acne, pigmentations, Cold Flu, Contraceptives, Ora solid and Liquid OTC dosages, and hair loss treatments sold under retail store brand names. Their products are FDA registered, WERCS-OSHA-certified, and compliant with California Prop-65.


AmWiner believes in protecting the planet, animal and plant kingdom  and holds this ethics dearly by creating products made to last with zero waste and zero animal cruelty.

For more information, email: o

Beard Mens Facial Hair Growth & Conditioning Gel-Maximum Strength 4-Months Supply

How does Beard Mens Facial Hair Growth & Conditioning Gel work?


Growing a luscious beard is a dream for many men. It not only enhances their appearance but also boosts their confidence. However, not everyone is blessed with fast-growing facial hair. This is where Beard Mens Facial Hair Growth & Conditioning Gel comes into play. This revolutionary product is designed to stimulate facial hair growth and condition the beard, giving you the luscious beard you've always desired.

The secret behind the effectiveness of Beard Mens Facial Hair Growth & Conditioning Gel lies in its unique formula. This gel is enriched with a blend of powerful ingredients that work together to promote hair growth and nourish the beard. One of the key ingredients is biotin, which is known for its hair-strengthening properties. Biotin helps to improve the health of the hair follicles, which in turn promotes faster and healthier hair growth.

Another important ingredient in Beard Mens Facial Hair Growth & Conditioning Gel is Minoxidil 5% and saw palmetto extract. Saw palmetto has been used for centuries to support healthy hair growth. It works by blocking the conversion of testosterone into dihydrotestosterone (DHT), a hormone that is known to contribute to hair loss. By reducing the levels of DHT in the body, saw palmetto helps to prevent hair loss and promote the growth of thicker, fuller facial hair.

To further enhance the effectiveness of Beard Mens Facial Hair Growth & Conditioning Gel, it also contains argan oil. Argan oil is rich in essential fatty acids and antioxidants, which nourish and moisturize the hair follicles. This helps to improve the overall health of the beard, making it softer, shinier, and more manageable. Additionally, argan oil helps to prevent breakage and split ends, allowing your beard to grow longer and stronger.

The key ingredients of Beard Mens Facial Hair Growth & Conditioning Gel

Beard Mens Facial Hair Growth & Conditioning Gel is packed with a powerful blend of natural ingredients that work together to stimulate facial hair growth and condition the beard. Here are the key ingredients that make this gel so effective:

  1. Biotin: Biotin, also known as vitamin B7, is a vital nutrient for hair growth. It strengthens the hair follicles, promotes hair growth, and improves the overall health of the beard.

  2. Saw Palmetto Extract: Saw palmetto extract is derived from the berries of the saw palmetto plant. It helps to block the conversion of testosterone into dihydrotestosterone (DHT), a hormone that contributes to hair loss.

  3. Argan Oil: Argan oil is rich in essential fatty acids and antioxidants, which nourish and moisturize the hair follicles. It improves the overall health of the beard, making it softer, shinier, and more manageable.

  4. Vitamin E: Vitamin E is a powerful antioxidant that helps to protect the hair follicles from damage caused by free radicals. It also promotes blood circulation in the scalp, which is essential for hair growth.

  5. Aloe Vera: Aloe vera has soothing and moisturizing properties that help to nourish the hair follicles and promote healthy hair growth. It also reduces itching and irritation, which are common problems faced by men growing a beard.

The benefits of using Beard Mens Facial Hair Growth & Conditioning Gel

Using Beard Mens Facial Hair Growth & Conditioning Gel offers a wide range of benefits for men looking to grow a luscious beard. Here are some of the key benefits you can expect from this amazing product:

  1. Faster Facial Hair Growth: The unique blend of ingredients in Beard Mens Facial Hair Growth & Conditioning Gel stimulates the hair follicles, promoting faster facial hair growth. You can expect to see significant improvements in the thickness and density of your beard within a few weeks of regular use.

  2. Thicker and Fuller Beard: The nourishing properties of Beard Mens Facial Hair Growth & Conditioning Gel help to improve the overall health of the beard, making it thicker and fuller. It strengthens the hair follicles, preventing breakage and promoting the growth of stronger, healthier facial hair.

  3. Soft and Manageable Beard: Beard Mens Facial Hair Growth & Conditioning Gel contains argan oil, which moisturizes and conditions the beard, making it soft and manageable. It reduces frizz and tangles, allowing you to style your beard effortlessly.

  4. Reduced Hair Loss: The saw palmetto extract in Beard Mens Facial Hair Growth & Conditioning Gel helps to block the conversion of testosterone into DHT, a hormone that contributes to hair loss. By reducing the levels of DHT in the body, this gel helps to prevent hair loss and promote the growth of thicker, healthier facial hair.

Conclusion: Embrace your luscious beard with Beard Mens Facial Hair Growth & Conditioning Gel

Growing a luscious beard has never been easier, thanks to Beard Mens Facial Hair Growth & Conditioning Gel. This revolutionary product is designed to stimulate facial hair growth and condition the beard, giving you the beard of your dreams. With its powerful blend of natural ingredients, Beard Mens Facial Hair Growth & Conditioning Gel promotes faster hair growth, strengthens the hair follicles, and nourishes the beard, making it thicker, fuller, and more manageable. Say goodbye to patchy beards and hello to a luscious beard with Beard Mens Facial Hair Growth & Conditioning Gel.

Clothing Company For Sale in USA

Women`s Apparel Manufacturing and Retail Store for Sale

Quality garment designers, fabrics, and apparel manufacturing company, for sale in Dallas Texas, the United States. Rapheeze clothing retail company is relocating to another country, closing their Dallas Texas stores. All inventories, sewing machines, store racks, counters, cash registers, SEO optimized websites, POS systems, store cameras, display shelves, and store fixtures, are available for sale at one bulk price. All offers will be greatly considered.
They operate full-service manufacturing, and distribution industry, manufacturing ethnic garments and fashion accessories for men and women of all ages.  A truckload of assorted fabrics, not displayed on their websites for making suits, men and women wears, are all in stock. Other African fabrics, genuine leather handbags, beach handbags sandals, jewelry, jewelry accessories, stones, pearls, beads, ropes, ornaments, and much more not displayed on the website are included in the sale. 
Their clothing fabrics are infused with UV 55 protection technology, to protect the skin from sun damage. The clothing materials are wrinkle-free and fade-resistant, guaranteed to remain the same any time, any year when cared for as directed.  The cotton materials are organically grown, hypo-allergenic, with temperature regulated system, that auto-adjust to climate conditions. 
They are a one-stop manufacturing factory created for New Age entrepreneurs, and businesses, who desire to develop new brands or expand their existing collections. Rapheeze will introduce their clothing design team to the new owner, their distributors, Macy's store buyers, and Nordstrom store buyers in the United States and Canada for continuous sale, without the hassles of marketing a new or fresh startup business.
Some of the distributors buying from Rapheeze are the wholesale fabrics Suppliers for African wax prints, printed color block fabrics, original hollandaise fabrics, Ghana Kente fabrics, cord laces, voile cord laces, and embroidered fabrics. They manufacture and distribute in wholesale trendy ethnic fashions, embroidery clothing, maxi skirts, long skirts, new designer fashions, long dresses, new fashion plus sizes, African clothes, African jewelry, jewelry accessories, and ethnic beads.   They are members of the World Trade American Chamber of Commerce, offering guaranteed delivery of exported merchandise to all countries. They have one of the most trusted and SEO-optimized robust websites, that has always worked for the success of retailers. They made sure to keep clothing stocks up to date with the trendy and finest clothing. 
They have expertise in all categories, and launch new styles every year, to catch up with new fashion trends. Rapheeze will continue to support and train the new management staff even after the company transfer till they become comfortable operating alone. 
Contact Rapheeze to schedule a tour today!.

U.S.A FDA Registered Minoxidil Manufacturing Laboratory

U.S.A Laboratory for Minoxidil Hair Loss Product Manufacturing

FDA Registered and GMP Certified Chemists

Raphe Pharmaceutique Laboratories is the No.1 USA minoxidil manufacturer, formulating original minoxidil products, topical Spironolactone products for hair loss treatments, topical solutions of finasteride for severe hair loss treatments, offering private label services on minoxidil foams and gel products.

Raphe Pharmaceutique laboratories manufacture topical, Dutasteride, and the new RU-58841 androgen receptor blocker, a topical ingredient for acne, androgen-mediated hair loss at (5% v/v). The product of choice for acne-prone skin, the most potent inhibitor of the sebaceous gland.

Raphe formulates hair loss treatment blend with natural herbal extracts, Peptide blends with Biotin, Ginseng Panax solutions for hair loss treatment and prevention, spironolactone blend with herbal extracts for ingrown female facial hair. Other contract manufactured and private label product formulations they offer are pain relief comfort gels, anti-bacterial anti-fungal preparations, natural skin bleaching, and depigmenting agents.

Raphe Pharmaceutique laboratory OTC drug products are produced under cGMP manufacturing standards and regulations with professionally trained scientists. FDA registered and state-licensed facility. Whether it`s a small project or a large formulation project, Raphe offers flexible solutions that enable companies to move their brands through each phase with efficiency and speed. Their early development solutions overcome complex formulation challenges such as bioavailability, solubility, and stability processes, navigating complex regulatory environment, build success for brands and enable commercial distribution to store, shorten timelines to getting to the market quicker.

Raphe conducts early stages of ingredients tests to define and establish product requirements and specifications. Conducts verification and validation testing essential to confirm that their products meet those specifications and its intended use for all Minoxidil, Finasteride, spironolactone, and hair loss treatment products, acne treatments and skin bleaching agents they manufacture.

Raphe Pharmaceutique Laboratories provide high-quality drug products to support the pursuit of regulatory approval, offering fit-for-purpose formulations for studies and a comprehensive range of finished forms. Raphe`s robust solutions include Hair loss product manufacturing at all scales, topical solutions with sustained bioavailability, quality design and product development, analytical and stability testing on finished products, Batch Registrations and, documentation for regulatory submissions.

Distributors has access to a range of formulation samples for evaluation purposes prior to final packaging. Each of Raphe`s development and manufacturing staffs are cGMP certified clinical experienced, provides fully integrated and customizable solutions that will drive speed, flexibility, and a streamlined supply chain.  All products they manufacture are evaluated for stability, efficacy, and shelf-life prior to distribution.

For contract manufacturing or private label of any hair loss product visit Healthcareprivatelabel

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